Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670701 | 0.91 | DRD2 (0.53) | DRD2CARM1POLBPRMT5WDR77 | |
| SCHEMBL28650984 | 0.81 | NPSR1 (0.44) | NPSR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL28654076 | 0.79 | HDAC4 (0.42) | DRD2PRMT5WDR77 | |
| SCHEMBL28656456 | 0.79 | POLB (0.48) | CARM1NPSR1POLBUSP2SMN1; SMN2 | |
| SCHEMBL28656457 | 0.79 | POLB (0.48) | CARM1NPSR1POLBUSP2SMN1; SMN2 | |
| SCHEMBL28668562 | 0.77 | DPP8 (0.48) | DPP8DPP9 | |
| SCHEMBL28669034 | 0.76 | NPSR1 (0.51) | NPSR1POLBUSP2SMN1; SMN2 | |
| SCHEMBL29758947 | 0.73 | PRMT5 (0.51) | DRD2CARM1POLBPRMT5WDR77 | |
| SCHEMBL28928597 | 0.73 | PRMT5 (0.51) | DRD2CARM1POLBPRMT5WDR77 | |
| SCHEMBL18212444 | 0.73 | PRMT5 (0.51) | DRD2CARM1POLBPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |