SCHEMBL2865757

SCHEMBL2865757

CC(C)C(C)COC(=O)c1ccccc1C(=O)OCC(C)C(C)C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.72
ALDH1A1 P00352 4/20 0.72
CYP3A4 P08684 3/20 0.53
CA2 P00918 1/20 0.53
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
TP53 P04637 2/20 0.49
MAPK1 P28482 1/20 0.49
ADRB2 P07550 5/20 0.48
ADRB1 P08588 5/20 0.48
ADRB3 P13945 5/20 0.48
LMNA P02545 1/20 0.47
NPC1 O15118 1/20 0.47
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525847 0.93 ALDH1A1 (0.64) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL4359463 0.93 ALDH1A1 (0.64) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL30525846 0.89 TSHR (0.63) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL6908488 0.85 TSHR (0.68) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL42787 0.84 ALDH1A1 (1.00) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL8144263 0.84 ALDH1A1 (1.00) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL29387332 0.84 ALDH1A1 (1.00) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL1754909 0.83 ALDH1A1 (0.65) TSHRALDH1A1TDP1MAPK1ADRB2
SCHEMBL8466969 0.82 TSHR (0.75) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL27494884 0.82 ALDH1A1 (0.96) TSHRALDH1A1CYP3A4CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
US-7619048-B2 Method for producing propylene polymer using alkoxysilane compound containing trialkysilyl group in molecular structure SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2009-11-17 US claimed
CN-118063652-A Process for producing propylene copolymers using catalyst systems with improved copolymerization activity 韩华道达尔能源有限公司 2024-05-24 CN disclosed
CN-117924563-A Solid catalyst for preparing polypropylene and method for preparing propylene derivative polymer 韩华道达尔能源有限公司 2024-04-26 CN disclosed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN disclosed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP disclosed
CN-111349185-B Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔能源有限公司 2023-02-03 CN disclosed
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN disclosed
CN-111349185-A Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔有限公司 2020-06-30 CN disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
US-7160949-B2 Olefin block copolymers, processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-01-09 US disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed
EP-1275670-B1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed
US-6583237-B1 Silyl-terminated olefin polymers; catalyst is transition metal cyclopentadiene compound, organoaluminum oxycompound, compounds that form an ion pair, organoaluminum compound, organosilicon compound, a dialkylzinc compound, and hydrogen MITSUI CHEMICALS, INC. (JP) 2003-06-24 US disclosed
US-20030055179-A1 Olefin block copolymers processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2003-03-20 US disclosed
EP-1275670-A1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2003-01-15 EP disclosed
EP-1270647-A1 BRANCHED POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING BRANCHED POLYOLEFIN Mitsui Chemicals, Inc. (JP) 2003-01-02 EP disclosed
EP-1092730-A1 PROCESS FOR PRODUCING OLEFIN POLYMER AND OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2001-04-18 EP disclosed