Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865757 | 0.85 | TSHR (0.72) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL4452946 | 0.84 | TSHR (0.70) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL29368000 | 0.81 | ALDH1A1 (0.76) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL420283 | 0.81 | ALDH1A1 (0.76) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL42787 | 0.81 | ALDH1A1 (1.00) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL29387332 | 0.81 | ALDH1A1 (1.00) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL8144263 | 0.81 | ALDH1A1 (1.00) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL15237076 | 0.80 | TSHR (0.65) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL8466969 | 0.79 | TSHR (0.75) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL27494884 | 0.79 | ALDH1A1 (0.96) | TSHRALDH1A1CYP3A4CA2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896969-B1 | Process for preparing solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization process | MITSUI CHEMICALS INC (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0896969-A1 | Process for preparing solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization process | Mitsui Chemicals, Inc. (JP) | 1999-02-17 | — | — | EP | disclosed |