Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 7/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27447132 | 0.89 | HTR2A (0.46) | GPR84HTR2AHTR2C | |
| SCHEMBL27526971 | 0.84 | NR4A2 (0.44) | GPR84HTR2A | |
| SCHEMBL27785494 | 0.83 | HTR2C (0.40) | HTR2AHTR2CHTR1A | |
| SCHEMBL27528319 | 0.83 | CYP2A6 (0.51) | — | |
| SCHEMBL27552422 | 0.83 | ALDH1A1 (0.35) | GPR84HTR2AHTR2C | |
| SCHEMBL28043663 | 0.83 | IMPDH2 (0.38) | GPR84HTR2AHTR2C | |
| SCHEMBL27550865 | 0.83 | NR4A2 (0.46) | GPR84TDO2HTR2A | |
| SCHEMBL28929780 | 0.82 | ALDH1A1 (0.57) | HTR2AHTR2CHTR1A | |
| SCHEMBL28293145 | 0.81 | KIF11 (0.37) | GPR84HTR1A | |
| SCHEMBL27891881 | 0.81 | ALDH1A1 (0.37) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |