Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 14/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659026 | 1.00 | HSD11B1 (0.37) | HSD11B1DPP4DPP7ALDH1A1CHRNB2 | |
| SCHEMBL20343540 | 0.80 | HSD11B1 (0.42) | HSD11B1DPP4DPP7CHRNB2CHRNA3 | |
| SCHEMBL28614554 | 0.77 | L3MBTL1 (0.43) | DPP4DPP7ALDH1A1 | |
| SCHEMBL28614556 | 0.77 | L3MBTL1 (0.43) | DPP4DPP7ALDH1A1 | |
| SCHEMBL18348011 | 0.76 | CHRNB2 (0.53) | HSD11B1DPP4DPP7ALDH1A1CHRNB2 | |
| SCHEMBL20343599 | 0.74 | HSD11B1 (0.44) | HSD11B1DPP4DPP7ALDH1A1CHRNB2 | |
| SCHEMBL20343439 | 0.74 | HSD11B1 (0.44) | HSD11B1DPP4DPP7ALDH1A1CHRNB2 | |
| SCHEMBL28670698 | 0.74 | ALDH1A1 (0.42) | HSD11B1ALDH1A1 | |
| SCHEMBL28670700 | 0.74 | ALDH1A1 (0.42) | HSD11B1ALDH1A1 | |
| SCHEMBL28811201 | 0.73 | ALDH1A1 (0.41) | DPP4DPP7ALDH1A1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |