Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | PTPN9 | P43378 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659460 | 0.87 | MEN1 (0.49) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28680692 | 0.85 | MEN1 (0.48) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28659185 | 0.85 | MEN1 (0.48) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28675671 | 0.85 | MEN1 (0.62) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28668413 | 0.84 | MEN1 (0.47) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28654877 | 0.81 | ADORA3 (0.52) | MEN1KMT2AHSP90AA1PTPN22PTPN11 | |
| SCHEMBL28677778 | 0.81 | PTPN22 (0.44) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28663886 | 0.77 | DHODH (0.41) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL29082654 | 0.75 | KMO (0.50) | MAPTPTPN1NPC1RAB9AKDM4E | |
| SCHEMBL28583437 | 0.72 | KDM4A (0.41) | MAPTKDM4EHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |