Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022955 | 0.87 | KDM4E (0.50) | ADORA3CYP3A4MAPTABCG2NPC1 | |
| SCHEMBL28659204 | 0.87 | GPR35 (0.48) | ADORA3CYP3A4MAPTABCG2NPC1 | |
| SCHEMBL28654875 | 0.87 | KDM4E (0.50) | ADORA3CYP3A4MAPTABCG2NPC1 | |
| SCHEMBL30022568 | 0.87 | GPR35 (0.48) | ADORA3CYP3A4MAPTABCG2NPC1 | |
| SCHEMBL19934809 | 0.85 | ADORA3 (0.48) | ADORA3CYP3A4MAPTABCG2TSHR | |
| SCHEMBL28654975 | 0.83 | MAPT (0.53) | ADORA3MAPTABCB1MEN1KMT2A | |
| SCHEMBL28668413 | 0.82 | MEN1 (0.47) | ADORA3CYP3A4MAPTTSHRNPC1 | |
| SCHEMBL30022887 | 0.82 | ALDH1A1 (0.50) | ADORA3CYP3A4MAPTABCG2ABCB1 | |
| SCHEMBL28659460 | 0.82 | MEN1 (0.49) | ADORA3CYP3A4MAPTNPC1ABCB1 | |
| SCHEMBL28659185 | 0.81 | MEN1 (0.48) | ADORA3CYP3A4MAPTNPC1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |