Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | PTPN9 | P43378 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023487 | 0.88 | DHODH (0.45) | MAPTSMN1; SMN2DHODHPTGS2ABCB1 | |
| SCHEMBL30022975 | 0.88 | PTGS2 (0.41) | MEN1KMT2AHSP90AA1ALDH1A1MAPT | |
| SCHEMBL30022887 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28659460 | 0.85 | MEN1 (0.49) | MEN1KMT2AHSP90AA1ALDH1A1MAPT | |
| SCHEMBL30023062 | 0.84 | MAPT (0.46) | ALDH1A1MAPTKDM4EHPGDPTPN22 | |
| SCHEMBL28659222 | 0.84 | MEN1 (0.48) | MEN1KMT2AHSP90AA1ALDH1A1MAPT | |
| SCHEMBL28680692 | 0.84 | MEN1 (0.48) | MEN1KMT2AHSP90AA1MAPTPTPN22 | |
| SCHEMBL28659185 | 0.84 | MEN1 (0.48) | MEN1KMT2AHSP90AA1ALDH1A1MAPT | |
| SCHEMBL28675671 | 0.84 | MEN1 (0.62) | MEN1KMT2AHSP90AA1ALDH1A1MAPT | |
| SCHEMBL30020913 | 0.83 | MAPT (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |