SCHEMBL28659972

SCHEMBL28659972

Cc1ccc(C2=Cc3c(ccc(C)c3-c3cccc4ccccc34)C2[Zr])o1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.34
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499694 0.88 DHFR (0.30) DHFR
SCHEMBL2237161 0.85 DHFR (0.36) DHFRTDP1
SCHEMBL22499655 0.82 PTGS1 (0.40)
SCHEMBL22499689 0.81 ALDH1A1 (0.34) CYP1A2TSHR
SCHEMBL2233784 0.80 DHFR (0.31) DHFR
SCHEMBL22499757 0.80 PTGS1 (0.39)
SCHEMBL28884670 0.79 DHFR (0.30) DHFR
Hydrochloric Acid SCHEMBL30312761 0.79 BRD4 (0.32) CYP1A2
SCHEMBL22499685 0.78 KDM4E (0.33) TDP1
SCHEMBL28678584 0.77 SLC9A1 (0.31) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631591-A Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer 日本聚丙烯株式会社 2021-11-09 CN disclosed