Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297206 | 0.88 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2NR1H4PPARG | |
| SCHEMBL2343630 | 0.86 | ALDH1A1 (0.70) | RAB9ANPC1SMN1; SMN2NR1H4PPARG | |
| SCHEMBL29661214 | 0.86 | ALDH1A1 (0.70) | RAB9ANPC1SMN1; SMN2NR1H4PPARG | |
| SCHEMBL29661189 | 0.79 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14859880 | 0.77 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL14859134 | 0.76 | NR1H4 (0.47) | RAB9ANPC1SMN1; SMN2NR1H4PPARG | |
| SCHEMBL28655554 | 0.75 | KCNK9 (0.67) | RAB9ANPC1SMN1; SMN2NR1H4KMT2A | |
| SCHEMBL28098740 | 0.75 | ATM (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL28269889 | 0.75 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7605360 | 0.74 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2NR1H4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | claimed |
| CN-113582969-B | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | disclosed |