SCHEMBL7605360

SCHEMBL7605360

CC(C)(C)c1ccc(NC(=O)NC(=O)c2c(F)cccc2F)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.65
MAPT P10636 4/20 0.65
GAA P10253 2/20 0.65
NPSR1 Q6W5P4 1/20 0.65
NPC1 O15118 4/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
HTT P42858 3/20 0.59
MAPK1 P28482 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
XBP1 P17861 1/20 0.59
EPHX2 P34913 1/20 0.50
NR1H4 Q96RI1 1/20 0.50
PKM P14618 1/20 0.49
TRPV1 Q8NER1 3/20 0.49
LMNA P02545 1/20 0.49
STAT1 P42224 1/20 0.49
SIRT1 Q96EB6 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC11 Q96DB2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Penfluron SCHEMBL117735 0.87 EPHX2 (0.60) RAB9AMAPTGAANPSR1NPC1
SCHEMBL8657575 0.84 SMN1; SMN2 (0.54) RAB9AMAPTGAANPSR1NPC1
SCHEMBL9326300 0.84 EPHX2 (0.57) RAB9AMAPTGAANPSR1NPC1
SCHEMBL13774579 0.84 MEN1 (0.63) RAB9AMAPTGAANPC1MEN1
SCHEMBL7604101 0.83 RAB9A (0.57) RAB9AMAPTGAANPC1MEN1
SCHEMBL7605653 0.83 RAB9A (0.65) RAB9AMAPTGAANPSR1NPC1
SCHEMBL10608014 0.82 MAOA (0.51) RAB9AMAPTGAANPC1MEN1
SCHEMBL11244486 0.81 RAB9A (0.55) RAB9AMAPTGAANPC1MEN1
SCHEMBL7605886 0.81 KMT2A (0.59) RAB9AMAPTGAANPC1MEN1
SCHEMBL10703352 0.81 KMT2A (0.53) RAB9AMAPTGAANPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
US-5142064-A Larvicides has benzoyl or thiobenzoyl group DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1992-08-25 US claimed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-4920135-A NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1990-04-24 US disclosed
US-4833151-A INTERFERES WITH METAMORPHOSES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-05-23 US disclosed
US-4607044-A Insecticidal use of ureas and thioureas DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1986-08-19 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 RAB9A 1813/4885MAPT 1882/4885GAA 1890/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 RAB9A 1813/4885MAPT 1882/4885GAA 1890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.