Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16563140 | 0.91 | BCHE (0.46) | BCHEACHEHTTCYP11B2KDM4E | |
| SCHEMBL18012027 | 0.89 | BCHE (0.47) | BCHEACHEHTTKDM4EHPGD | |
| SCHEMBL19441776 | 0.76 | BCHE (0.39) | BCHEACHERAB9AMAPTKDM4E | |
| SCHEMBL18012043 | 0.76 | BCHE (0.41) | BCHEACHEHTTTSHR | |
| SCHEMBL17996794 | 0.76 | BCHE (0.41) | BCHEACHETSHR | |
| SCHEMBL16563147 | 0.75 | BCHE (0.38) | BCHEACHETSHR | |
| SCHEMBL19441771 | 0.74 | BCHE (0.38) | BCHEACHERAB9ALMNAMAPT | |
| SCHEMBL18011991 | 0.73 | BCHE (0.41) | BCHEACHETSHR | |
| Hydrochloric Acid SCHEMBL2462166 | 0.71 | IMPDH2 (0.42) | BCHEACHEMAPTNCOA3KDM4E | |
| SCHEMBL3224025 | 0.71 | ESR2 (0.60) | NOTUMGSK3AGSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098582-B1 | FUNCTIONAL ELECTRODE AND FUNCTIONAL ELECTROCHROMIC DEVICE | RICOH CO LTD (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-7830584-B2 | Organic-inorganic composite material and method for producing the same, and functional electrode and functional device | RICOH COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-2098582-A1 | ORGANIC INORGANIC COMPOSITE MATERIAL, PROCESS FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | Ricoh Company, Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | RICOH COMPANY, LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | EPCAM, ILK, L1CAM | ACHE 605/4885BCHE 1938/4885NOTUM 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.