Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 8/20 | 0.37 |
| ▸ | ANPEP | P15144 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29835052 | 0.85 | ADORA2A (0.38) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL26981136 | 0.85 | ADORA2A (0.38) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL30950292 | 0.83 | TARS1 (0.37) | SLC29A1 | |
| SCHEMBL29401884 | 0.78 | ADORA3 (0.53) | ADORA2AADORA2BSMN1; SMN2PI4KAPI4K2B | |
| SCHEMBL3831039 | 0.78 | ADORA3 (0.53) | ADORA2AADORA2BSMN1; SMN2PI4KAPI4K2B | |
| SCHEMBL31228871 | 0.77 | NPEPPS (0.35) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL29089559 | 0.76 | ADORA2A (0.64) | ADORA2AADORA2BNPEPPSSMN1; SMN2PI4KA | |
| SCHEMBL29089554 | 0.76 | ADORA2A (0.64) | ADORA2AADORA2BNPEPPSSMN1; SMN2PI4KA | |
| SCHEMBL30968983 | 0.74 | RXFP1 (0.39) | ADORA2AADORA2BTP53LMNAHTT | |
| SCHEMBL29238711 | 0.73 | HTR2B (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113840926-A | Method for preparing lipid-encapsulated RNA nanoparticles | 阿克丘勒斯治疗公司 | 2021-12-24 | — | — | CN | disclosed |