Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033940 | 0.91 | LMNA (0.40) | RXFP1LMNATP53ALOX15TSHR | |
| SCHEMBL30950292 | 0.85 | TARS1 (0.37) | SLC29A1ADORA1 | |
| SCHEMBL17627818 | 0.84 | RXFP1 (0.39) | RXFP1LMNATP53ALOX15TSHR | |
| SCHEMBL30705001 | 0.84 | RXFP1 (0.39) | RXFP1LMNATP53ALOX15TSHR | |
| SCHEMBL31031049 | 0.82 | SLC29A1 (0.39) | RXFP1LMNATSHRADORA2AADORA2B | |
| SCHEMBL29401884 | 0.82 | ADORA3 (0.53) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL3831039 | 0.82 | ADORA3 (0.53) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL28662239 | 0.74 | ADORA2A (0.38) | LMNATP53HTTADORA2AADORA2B | |
| SCHEMBL28758971 | 0.73 | ADORA2A (0.65) | RXFP1LMNATSHRHTTADORA2A | |
| SCHEMBL29137662 | 0.73 | SLC29A1 (0.42) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251494-A | Compositions and methods for modulating KRAS expression | 美国微哲默理有限责任公司 | 2024-06-25 | — | — | CN | disclosed |