Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 8/20 | 0.38 |
| ▸ | ANPEP | P15144 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981136 | 1.00 | ADORA2A (0.38) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL31228871 | 0.90 | NPEPPS (0.35) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL31406536 | 0.87 | ADORA2A (0.36) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL28344455 | 0.87 | ADORA2A (0.36) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL29043762 | 0.86 | KDM4E (0.31) | NPEPPSANPEP | |
| SCHEMBL29407144 | 0.86 | KDM4E (0.31) | NPEPPSANPEP | |
| SCHEMBL28662239 | 0.85 | ADORA2A (0.38) | ADORA2AADORA2BNPEPPSANPEPSMN1; SMN2 | |
| SCHEMBL16987222 | 0.82 | TARS1 (0.38) | TP53LMNAHTT | |
| SCHEMBL29435121 | 0.82 | TARS1 (0.38) | TP53LMNAHTT | |
| SCHEMBL28564130 | 0.82 | TARS1 (0.38) | TP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115943307-A | MR1 ligands and pharmaceutical compositions for immunomodulation | 巴塞尔大学 | 2023-04-07 | — | — | CN | claimed |
| EP-4736871-A1 | RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINE | Shenzhen Shenxin Biotechnology Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-4398884-A1 | UNIVERSAL INFLUENZA VACCINE AND METHODS OF USE | The Trustees of the University of Pennsylvania (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-117866948-A | Negative selection method and system for purifying circular nucleic acid | 上海环码生物医药有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117460518-A | CD-90 targeted lipid nanoparticles | 宾夕法尼亚大学理事会 | 2024-01-26 | — | — | CN | disclosed |
| CN-117425496-A | Lipid nanoparticle therapy to evade immune responses | 宾夕法尼亚大学理事会 | 2024-01-19 | — | — | CN | disclosed |
| CN-117413065-A | Constructs, methods and uses for the preparation of circular RNAs | 上海环码生物医药有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117396194-A | Targeted therapeutic lipid nanoparticles and methods of use | 宾夕法尼亚大学理事会 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396604-A | Compositions and methods for targeting lipid nanoparticle therapies to stem cells | 宾夕法尼亚大学理事会 | 2024-01-12 | — | — | CN | disclosed |
| CN-117042780-A | In vivo targeting of T cells for mRNA therapeutic agents | 宾夕法尼亚大学理事会 | 2023-11-10 | — | — | CN | disclosed |
| CN-116546991-A | mRNA therapeutic agent versus CD4 + In vivo targeting of T cells | 宾夕法尼亚大学理事会 | 2023-08-04 | — | — | CN | disclosed |
| CN-116322788-A | Cyclic RNA compositions and methods | 奥纳治疗公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116113419-A | Cyclic RNA compositions and methods | 奥纳治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116034114-A | Cyclic RNA compositions and methods | 奥纳治疗公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-114096550-B | Modified nucleosides and methods of synthesis thereof | 斯微(上海)生物科技股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115943307-A | MR1 ligands and pharmaceutical compositions for immunomodulation | 巴塞尔大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115867291-A | Circular RNA compositions and methods | 麻省理工学院 | 2023-03-28 | — | — | CN | disclosed |
| WO-2023039396-A1 | UNIVERSAL INFLUENZA VACCINE AND METHODS OF USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-03-16 | — | — | WO | disclosed |
| CN-115484990-A | Composition for inducing apoptosis having genomic sequence variation and method for inducing apoptosis using the same | 基础科学研究院 | 2022-12-16 | — | — | CN | disclosed |
| CN-115052635-A | Circular RNA compositions and methods | 奥纳治疗公司 | 2022-09-13 | — | — | CN | disclosed |