Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483415 | 0.83 | NPSR1 (0.44) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL3239982 | 0.83 | NPSR1 (0.44) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL2394240 | 0.81 | NPSR1 (0.43) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL437417 | 0.79 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL9134202 | 0.79 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL3237294 | 0.79 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL11011944 | 0.79 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL28249141 | 0.78 | ALDH1A1 (0.40) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL4560019 | 0.78 | L3MBTL1 (0.46) | NPSR1ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL15611386 | 0.78 | NPSR1 (0.40) | NPSR1ALDH1A1TSHRGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202238-A1 | Nucleotide Compounds including a rigid linker | Applied Biosystems, LLC (US) | 2010-06-30 | — | — | EP | disclosed |
| EP-1121371-B8 | NUCLEOTIDE COMPOUNDS INCLUDING A RIGID LINKER | APPLIED BIOSYSTEMS LLC (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-1121371-B1 | NUCLEOTIDE COMPOUNDS INCLUDING A RIGID LINKER | APPLIED BIOSYSTEMS LLC (US) | 2009-05-27 | — | — | EP | disclosed |
| US-6653462-B2 | Useful as substrates for polymerases and in primer extension; mutants | APPLERA CORPORATION | 2003-11-25 | — | — | US | disclosed |
| US-20020151711-A1 | Nucleotide compounds including a rigid linker | PE CORPORATION (NY) (US) | 2002-10-17 | — | — | US | disclosed |
| EP-1121371-A1 | NUCLEOTIDE COMPOUNDS INCLUDING A RIGID LINKER | Applera Corporation (US) | 2001-08-08 | — | — | EP | disclosed |
| EP-0834499-B1 | Process for the preparation of aromatic vinyl compounds | DAINIPPON INK & CHEMICALS (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6197555-B1 | PRIMER EXTENSION REACTION USING NUCLEOTIDE OF DEFINED STRUCTURE; FOR SANGER-TYPE SEQUENCING REACTIONS WITH EVEN DISTRIBUTION OF PEAK HEIGHTS | THE PERKIN-ELMER CORPORATION | 2001-03-06 | — | — | US | disclosed |
| WO-2000021974-A1 | NUCLEOTIDE COMPOUNDS INCLUDING A RIGID LINKER | THE PERKIN-ELMER CORPORATION (US) | 2000-04-20 | — | — | WO | disclosed |
| EP-0834499-A1 | Process for the preparation of aromatic vinyl compounds | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151711-A1 | Nucleotide compounds including a rigid linker | TYMP, PNP, DCTD | NPSR1 3107/4885ALDH1A1 3227/4885TSHR 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.