Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470051 | 0.84 | HTT (0.57) | TDP1RAB9AALDH1A1KMT2ANPSR1 | |
| SCHEMBL4559813 | 0.82 | L3MBTL1 (0.41) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL10566627 | 0.82 | L3MBTL1 (0.47) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL483415 | 0.81 | NPSR1 (0.44) | L3MBTL1TDP1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11682975 | 0.80 | SMN1; SMN2 (0.46) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL2394240 | 0.79 | NPSR1 (0.43) | L3MBTL1TDP1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2866274 | 0.78 | NPSR1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL11011944 | 0.78 | NPSR1 (0.41) | L3MBTL1TDP1RAB9AADRA2CALDH1A1 | |
| SCHEMBL14463252 | 0.77 | RAB9A (0.43) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL11225960 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TDP1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039903-B1 | 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF | SUNTORY KABUSHIKI KAISHA (JP) | 1986-04-09 | — | — | EP | claimed |
| US-9563075-B2 | Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate | Konica Minolta, Inc. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-8632863-B2 | Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20130222720-A1 | METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE | KONICA MINOLTA , INC. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20120327343-A1 | POLYMER FILM, OPTICALLY-COMPENSATORY FILM, PROCESS FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2012-12-27 | — | — | US | disclosed |
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | L3MBTL1 2665/4885TDP1 3892/4885RAB9A 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.