Biphenyl

Biphenyl

SCHEMBL8999030

CO[SiH2]OC.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
SLC22A2 O15244 1/20 0.42
SLC22A1 O15245 1/20 0.42
SLC22A3 O75751 1/20 0.42
SLC6A4 P31645 1/20 0.42
CA4 P22748 1/20 0.41
TAAR1 Q96RJ0 2/20 0.41
PDE4B Q07343 2/20 0.41
CYP1A2 P05177 2/20 0.39
MAPK1 P28482 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOTUM Q6P988 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
MAPT P10636 3/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL63645 1.00 ALDH1A1 (0.53) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL28662908 0.87 PTGS2 (0.43) ALDH1A1MAPK1HSD17B10BCL2L1MAPT
Biphenyl SCHEMBL15542338 0.82 ALDH1A1 (0.53) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL3301393 0.81 ALDH1A1 (0.39) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL3908169 0.81 ALDH1A1 (0.69) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL28881047 0.81 ALDH1A1 (0.69) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Toluene SCHEMBL29169581 0.80 ACHE (0.61) CA4TDP1MEN1TSHRKMT2A
Naphthalene SCHEMBL28218833 0.79 CYP2A6 (0.50) ALDH1A1CA4CYP1A2MAPK1CYP3A4
Fluorobenzene SCHEMBL28054128 0.78 CA4 (0.38) SLC6A4CA4CYP1A2TDP1TSHR
Phenol SCHEMBL28247126 0.78 CA4 (0.58) ALDH1A1CA4PDE4BCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492966-B1 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS AS (DK) 1996-08-21 EP disclosed
US-5227355-A STEREOSPECIFIC CATALYST SYSTEM INTENDED FOR THE POLYMERIZATION OF OLEFINS Seppala, Jukka (FI) 1993-07-13 US disclosed
EP-0492966-A2 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS A/S (DK) 1992-07-01 EP disclosed