Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | SULT1A1 | P50225 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664679 | 0.84 | SMN1; SMN2 (0.50) | GAACA1CA2CA4APP | |
| SCHEMBL3709201 | 0.83 | RAB9A (0.51) | HTTDYRK1AAPPCYP1A2CYP3A4 | |
| SCHEMBL6632291 | 0.79 | CYP1A2 (0.54) | GAACA1CA2CA12CA4 | |
| SCHEMBL29248357 | 0.79 | ALDH1A1 (0.44) | GAACA1CA2CA12CA9 | |
| SCHEMBL28930490 | 0.79 | ALDH1A1 (0.59) | HTTCA2CA5ADYRK1ACYP3A4 | |
| SCHEMBL23249736 | 0.77 | GAA (0.47) | HTTGAAL3MBTL1DYRK1AAPP | |
| SCHEMBL28588889 | 0.77 | NPC1 (0.60) | GAACA1CA2CA12DYRK1A | |
| SCHEMBL27689304 | 0.77 | DYRK1A (0.49) | HTTGAAL3MBTL1CA1CA2 | |
| SCHEMBL2763498 | 0.76 | CYP2C9 (0.36) | CA2CA5ADYRK1ACYP1A2CYP3A4 | |
| SCHEMBL20509400 | 0.76 | L3MBTL1 (0.51) | HTTGAAL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273019-A | Novel benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use especially as C-Met inhibitors | AVENTIS PHARMA SA (FR) | 2008-09-24 | — | — | CN | disclosed |