Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467015 | 0.89 | PRKCI (0.43) | HSD11B1CA5AALDH1A1CYP3A4LMNA | |
| SCHEMBL3854731 | 0.87 | CA5A (0.40) | HSD11B1CA5AALDH1A1CYP3A4LMNA | |
| SCHEMBL8431166 | 0.86 | CA1 (0.47) | HSD11B1CA5AALDH1A1CYP3A4CA1 | |
| SCHEMBL5166345 | 0.81 | NPFFR2 (0.44) | HSD11B1 | |
| SCHEMBL31749059 | 0.81 | NPFFR2 (0.44) | HSD11B1 | |
| SCHEMBL8934245 | 0.81 | HSD11B1 (0.36) | HSD11B1CA5AALDH1A1KDM4EGAA | |
| SCHEMBL5981527 | 0.80 | HSD11B1 (0.52) | HSD11B1ALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL7779178 | 0.80 | CA5A (0.50) | CA5AALDH1A1CYP3A4LMNATTR | |
| SCHEMBL3002757 | 0.78 | HSD11B1 (0.50) | HSD11B1ALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL3243039 | 0.78 | TTR (0.62) | CA5AALDH1A1CYP3A4LMNATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929276-B | Method for preparing pyrimidine compounds from methyl ketone compounds and nitrile compounds | 湖南大学 | 2021-08-31 | — | — | CN | claimed |
| CN-109096126-B | Deuterium labeled D9Synthesis method of clenbuterol hydrochloride | 东莞暨南大学研究院 | 2021-03-26 | — | — | CN | claimed |
| CN-105968021-A | Stable isotope labeling Clenproperol compound and synthesis method thereof | 上海化工研究院 | 2016-09-28 | — | — | CN | claimed |
| US-20240051916-A1 | METHOD FOR PRODUCING N-(HETERO)ARYL (METH)ACRYLAMIDE COMPOUND | FUJIFILM CORPORATION (JP) | 2024-02-15 | — | — | US | disclosed |
| CN-117398332-A | Keli boron Luo Ruangao | 杭州中美华东制药有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117242052-A | Method for producing N- (hetero) aryl (meth) acrylamide compound | 富士胶片株式会社 | 2023-12-15 | — | — | CN | disclosed |
| WO-2022249994-A1 | METHOD FOR PRODUCING N-(HETERO)ARYL(METH)ACRYLAMIDE COMPOUNDS | 富士フイルム株式会社 | 2022-12-01 | — | — | WO | disclosed |
| CN-109912434-B | Synthesis method of phenylethanolamine beta receptor agonist | 上海安谱实验科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-108929276-B | Method for preparing pyrimidine compounds from methyl ketone compounds and nitrile compounds | 湖南大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-113061096-A | Preparation method of stable isotope labeled krusel | 阿尔塔(天津)标准物质研究院有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-109096126-B | Deuterium labeled D9Synthesis method of clenbuterol hydrochloride | 东莞暨南大学研究院 | 2021-03-26 | — | — | CN | disclosed |
| US-4323575-A | TOPICAL ANTIINFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-06 | — | — | US | disclosed |
| US-4237048-A | COLORFASTNESS; FOR DYEING NATURAL AND SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0019411-A1 | 1-Phenyl-2-aminoethanol derivatives, processes for their manufacture and pharmaceutical compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-11-26 | — | — | EP | disclosed |
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| EP-0000809-A1 | Anti-inflammatory 1-phenylethanolamine derivatives, pharmaceutical compositions thereof and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-02-21 | — | — | EP | disclosed |
| US-4105655-A | PHENYL-AZO-ANILINO DYESTUFF | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4083844-A | Phenylazo orthocyano phenylazo or orthocyano phenylazo phenylazo containing dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |
| US-3962209-A | PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051916-A1 | METHOD FOR PRODUCING N-(HETERO)ARYL (METH)ACRYLAMIDE COMPOUND | NAT1, AHR, PAM | HSD11B1 473/4885CA5A 3814/4885ALDH1A1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.