Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866567 | 0.81 | HSD11B1 (0.48) | HSD11B1CA5AKDM4EALDH1A1GAA | |
| SCHEMBL10493912 | 0.80 | HSD11B1 (0.34) | HSD11B1S1PR3SLC22A12MEN1KMT2A | |
| SCHEMBL5163409 | 0.79 | ADRB2 (0.43) | CA5ACYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL5683009 | 0.79 | CYP11B2 (0.43) | CA5AS1PR3CYP11B1CYP11B2MEN1 | |
| SCHEMBL6478409 | 0.79 | GSK3B (0.46) | HSD11B1S1PR3SLC22A12KDM4EALDH1A1 | |
| SCHEMBL10467015 | 0.76 | PRKCI (0.43) | HSD11B1CA5AMEN1KMT2AKDM4E | |
| SCHEMBL11643153 | 0.75 | ADRB2 (0.39) | S1PR3MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11643593 | 0.75 | ADRB2 (0.38) | HSD11B1S1PR3MEN1KMT2AKDM4E | |
| SCHEMBL24494667 | 0.75 | VCAM1 (0.46) | USP7S1PR3CYP11B1CYP11B2SLC22A12 | |
| SCHEMBL5899647 | 0.75 | S1PR3 (0.52) | S1PR3CYP11B1CYP11B2ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031466-A1 | NEW ETHANOLAMINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 1996-10-10 | — | — | WO | disclosed |