Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2866132 | 0.89 | CNR1 (0.31) | LMNA | |
| Hydrochloric Acid SCHEMBL2871037 | 0.89 | CNR1 (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL3375981 | 0.88 | NPC1 (0.33) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL2870726 | 0.88 | RXRA (0.35) | — | |
| Hydrochloric Acid SCHEMBL2858707 | 0.88 | RXRA (0.38) | — | |
| Hydrochloric Acid SCHEMBL2861479 | 0.88 | LMNA (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL2867837 | 0.87 | LMNA (0.31) | LMNA | |
| Hydrochloric Acid SCHEMBL2862486 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2857221 | 0.84 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2861109 | 0.84 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024185503-A1 | RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME | 東ソー株式会社 | 2024-09-12 | — | — | WO | disclosed |
| EP-3020736-B1 | ULTRA-HIGH-MOLECULAR-WEIGHT POLYETHYLENE PARTICLES AND MOLDED BODY COMPRISING SAME | TOSOH CORP (JP) | 2020-09-09 | — | — | EP | disclosed |
| US-10340492-B2 | Ultrahigh molecular weight polyethylene stretched porous film | TOSOH CORPORATION (JP) | 2019-07-02 | — | — | US | disclosed |
| US-10316119-B2 | Ultrahigh molecular weight polyethylene particles and molded product made thereof | TOSOH CORPORATION (JP) | 2019-06-11 | — | — | US | disclosed |
| EP-1964860-B1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | TOSOH CORP (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-20170125763-A1 | ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE STRETCHED POROUS FILM | TOSOH CORPORATION (JP) | 2017-05-04 | — | — | US | disclosed |
| US-20160152744-A1 | ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE PARTICLES AND MOLDED PRODUCT MADE THEREOF | TOSOH CORPORATION (JP) | 2016-06-02 | — | — | US | disclosed |
| EP-3020736-A1 | ULTRA-HIGH-MOLECULAR-WEIGHT POLYETHYLENE PARTICLES AND MOLDED BODY COMPRISING SAME | Tosoh Corporation (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-1473323-B1 | Polyethylene composition and process for producing same | TOSOH CORP (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-7838611-B2 | Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer | TOSOH CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-7678866-B2 | Polyethylene composition and process for producing same | TOSOH CORPORATION (JP) | 2010-03-16 | — | — | US | disclosed |
| US-20090137755-A1 | ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER | TOSOH CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1473323-A1 | Polyethylene composition and process for producing same | Tosoh Corporation (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20040214953-A1 | Polyethylene composition and process for producing same | TOSOH CORPORATION | 2004-10-28 | — | — | US | disclosed |