Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | PTPN9 | P43378 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669959 | 0.84 | MEN1 (0.42) | MEN1KMT2AHSP90AA1POLBPTPN22 | |
| SCHEMBL28659185 | 0.76 | MEN1 (0.48) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL10014227 | 0.76 | TNK2 (0.47) | MEN1KMT2AHSP90AA1BLMPOLB | |
| SCHEMBL28675671 | 0.73 | MEN1 (0.62) | MEN1KMT2AHSP90AA1BLMPTPN22 | |
| SCHEMBL28658459 | 0.73 | ALDH1A1 (0.53) | HTTRECQLBCL9CTNNB1GPR35 | |
| SCHEMBL28659460 | 0.71 | MEN1 (0.49) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28659222 | 0.70 | MEN1 (0.48) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28680692 | 0.70 | MEN1 (0.48) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL28668413 | 0.69 | MEN1 (0.47) | MEN1KMT2AHSP90AA1PTPN22PTPRC | |
| SCHEMBL4387282 | 0.65 | PRNP (0.42) | AKR1C3AKR1C2AKR1C1AKR1C4ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |