Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | PTPN9 | P43378 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.39 |
| ▸ | HNF4A | P41235 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668792 | 0.84 | MEN1 (0.42) | MEN1HSP90AA1KMT2APTPN22PTPRC | |
| SCHEMBL28658459 | 0.75 | ALDH1A1 (0.53) | ABCB1BCL9CTNNB1KDM4EGAA | |
| SCHEMBL28668413 | 0.75 | MEN1 (0.47) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL28675671 | 0.73 | MEN1 (0.62) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL28659460 | 0.71 | MEN1 (0.49) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL28659185 | 0.70 | MEN1 (0.48) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL28680692 | 0.70 | MEN1 (0.48) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL28659222 | 0.70 | MEN1 (0.48) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL28654877 | 0.69 | ADORA3 (0.52) | MEN1HSP90AA1KMT2AMAOAPTPN22 | |
| SCHEMBL10550546 | 0.67 | LMNA (0.51) | MEN1KMT2ACA12CA9MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |