Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F9 | P00740 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670100 | 1.00 | KCNN4 (0.37) | KCNN4F2F9F10F12 | |
| SCHEMBL29262043 | 0.88 | ALDH1A1 (0.42) | KCNN4ALDH1A1PDE2ALMNANPSR1 | |
| SCHEMBL22470105 | 0.88 | ALDH1A1 (0.42) | KCNN4ALDH1A1PDE2ALMNANPSR1 | |
| SCHEMBL22470470 | 0.87 | F2 (0.38) | KCNN4F2F9F10F12 | |
| SCHEMBL22470473 | 0.87 | F2 (0.38) | KCNN4F2F9F10F12 | |
| SCHEMBL29261962 | 0.83 | IL1B (0.42) | KCNN4IL1BP2RX7NR1H2NR1H3 | |
| SCHEMBL29261963 | 0.83 | IL1B (0.42) | KCNN4IL1BP2RX7NR1H2NR1H3 | |
| SCHEMBL29355246 | 0.83 | IL1B (0.42) | KCNN4IL1BP2RX7NR1H2NR1H3 | |
| SCHEMBL30823530 | 0.81 | NPC1 (0.40) | ALDH1A1LGMNIL1BP2RX7LMNA | |
| SCHEMBL22470118 | 0.76 | KCNN4 (0.42) | KCNN4ALDH1A1PDE2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |