SCHEMBL28670458

SCHEMBL28670458

CCc1cc(C)cc(CC)c1C[C]=O

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
PPARG P37231 1/20 0.30
HTT P42858 1/20 0.30
MAPK10 P53779 1/20 0.30
NCOA2 Q15596 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509853 0.80 THRB (0.34) KMT2AALDH1A1GAAHTT
SCHEMBL3025730 0.78 DHFR (0.36) KMT2ASMN1; SMN2HSD17B10ALDH1A1GAA
SCHEMBL97783 0.76 HRH3 (0.36) KMT2ASMN1; SMN2HSD17B10HPGD
SCHEMBL1262846 0.75 KMT2A (0.36) KMT2ASMN1; SMN2ALDH1A1GAAHPGD
SCHEMBL15133742 0.73 AKR1C3 (0.32) KMT2ASMN1; SMN2HSD17B10ALDH1A1GAA
SCHEMBL508950 0.71 ALDH1A1 (0.38) KMT2ASMN1; SMN2HSD17B10ALDH1A1GAA
SCHEMBL27057362 0.71 KMT2A (0.32) KMT2AALDH1A1GAAHPGDMAPK1
SCHEMBL509831 0.71 KMT2A (0.35) KMT2AALDH1A1GAAHPGDMAPK1
SCHEMBL1224583 0.71 KMT2A (0.32) KMT2AALDH1A1GAAHPGDMAPK1
SCHEMBL18966864 0.71 KMT2A (0.40) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330422-B Preparation method of 2, 6-diethyl-4-methylphenylacetic acid 江苏中旗科技股份有限公司 2022-05-10 CN claimed
CN-110330422-B Preparation method of 2, 6-diethyl-4-methylphenylacetic acid 江苏中旗科技股份有限公司 2022-05-10 CN disclosed
CN-110330422-B Preparation method of 2, 6-diethyl-4-methylphenylacetic acid 江苏中旗科技股份有限公司 2022-05-10 CN disclosed
CN-113121341-A Method for synthesizing 2, 6-diethyl-4-methyl phenylacetate 江苏中旗科技股份有限公司 2021-07-16 CN disclosed