Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833968 | 0.91 | PGR (0.46) | IL1BPGRNR3C2ARNR3C1 | |
| SCHEMBL22655173 | 0.77 | IL1B (0.62) | IL1BTNFEDNRA | |
| SCHEMBL22655174 | 0.77 | IL1B (0.62) | IL1BTNFEDNRA | |
| SCHEMBL29325946 | 0.72 | PGR (0.36) | PGRNR3C2ARNR3C1 | |
| SCHEMBL30833991 | 0.70 | IL1B (0.45) | IL1BTNF | |
| SCHEMBL30833874 | 0.70 | IL1B (0.45) | IL1BTNF | |
| SCHEMBL26943723 | 0.70 | IL1B (0.45) | IL1BTNF | |
| SCHEMBL25297096 | 0.68 | IL1B (0.48) | IL1B | |
| SCHEMBL25252231 | 0.68 | IL1B (0.48) | IL1B | |
| Hydrochloric Acid SCHEMBL31057109 | 0.67 | IL1B (0.47) | IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784957-A | NLRP3 inflammasome inhibitor | 诺华股份有限公司 | 2021-12-10 | — | — | CN | disclosed |