Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670710 | 0.91 | IL1B (0.39) | PGRNR3C2ARNR3C1IL1B | |
| SCHEMBL29325917 | 0.76 | PGR (0.44) | PGRNR3C2ARNR3C1TRPA1 | |
| SCHEMBL30157150 | 0.74 | PGR (0.43) | PGRNR3C2ARNR3C1TRPA1 | |
| SCHEMBL22655173 | 0.73 | IL1B (0.62) | IL1BKCNH2TNFNLRP3 | |
| SCHEMBL22655174 | 0.73 | IL1B (0.62) | IL1BKCNH2TNFNLRP3 | |
| SCHEMBL26943723 | 0.72 | IL1B (0.45) | IL1BCYP2D6SYKKCNH2TNF | |
| SCHEMBL30833991 | 0.72 | IL1B (0.45) | IL1BCYP2D6SYKKCNH2TNF | |
| SCHEMBL30833874 | 0.72 | IL1B (0.45) | IL1BCYP2D6SYKKCNH2TNF | |
| SCHEMBL30834033 | 0.72 | IL1B (0.46) | PGRNR3C2ARIL1BCHRM1 | |
| SCHEMBL29325946 | 0.67 | PGR (0.36) | PGRNR3C2ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |