SCHEMBL28670823

SCHEMBL28670823

CCC(OC)O[SiH2]C(C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TRPA1 O75762 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
ALDH1A1 P00352 2/20 0.33
THRB P10828 1/20 0.33
CYP3A4 P08684 2/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CHRM1 P11229 1/20 0.33
SMPD1 P17405 1/20 0.33
DRD1 P21728 1/20 0.33
TBXA2R P21731 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28676080 0.85 LMNA (0.36) LMNAMEN1KMT2ATRPA1TAAR1
SCHEMBL22661048 0.81 LMNA (0.44) LMNAMEN1KMT2ATRPA1CHRM2
SCHEMBL28693715 0.78 ALDH1A1 (0.37) LMNAKMT2ATAAR1ALDH1A1THRB
SCHEMBL3295140 0.74 LMNA (0.33) LMNAKMT2AHTT
SCHEMBL28945600 0.73 LMNA (0.40) LMNAMEN1KMT2ATRPA1ALDH1A1
SCHEMBL7587891 0.73 ALDH1A1 (0.41) LMNAMEN1KMT2ATAAR1ALDH1A1
SCHEMBL3157665 0.71 CYP2D6 (0.38) LMNAMEN1KMT2ATAAR1ALDH1A1
SCHEMBL28449357 0.71
SCHEMBL22661012 0.70 TP53 (0.35) KMT2ATRPA1HTTSIGMAR1
SCHEMBL28457368 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250754-B Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2022-01-25 CN disclosed