SCHEMBL7587891

SCHEMBL7587891

CO[SiH2]C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
KMT2A Q03164 2/20 0.39
TAAR1 Q96RJ0 3/20 0.38
THRB P10828 1/20 0.37
ADRA2A P08913 2/20 0.37
CYP2D6 P10635 2/20 0.37
LMNA P02545 2/20 0.37
ADRA2C P18825 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 2/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
SMPD1 P17405 1/20 0.36
DRD1 P21728 1/20 0.36
TBXA2R P21731 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3157665 0.79 CYP2D6 (0.38) ALDH1A1KMT2ATAAR1ADRA2ACYP2D6
SCHEMBL28693715 0.79 ALDH1A1 (0.37) ALDH1A1KMT2ATAAR1THRBADRA2A
SCHEMBL704150 0.78 KMT2A (0.40) ALDH1A1KMT2ATAAR1THRBADRA2A
SCHEMBL8142566 0.76 SLC6A4 (0.40) ALDH1A1KMT2ATAAR1ADRA2ACYP2D6
SCHEMBL8849310 0.71 KMT2A (0.35) ALDH1A1KMT2ATAAR1THRBADRA2A
SCHEMBL28410419 0.71 LMNA (0.43) KMT2ATAAR1LMNAL3MBTL1MEN1
SCHEMBL11050395 0.70 ALOX5 (0.42) ALDH1A1TAAR1ADRA2ACYP2D6LMNA
SCHEMBL11050400 0.70 ADRA2C (0.44) ALDH1A1KMT2ATAAR1ADRA2ACYP2D6
SCHEMBL8384502 0.70 TAAR1 (0.41) ALDH1A1TAAR1ADRA2ACYP2D6LMNA
SCHEMBL8463424 0.70 TSHR (0.43) ALDH1A1TAAR1ADRA2ACYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1189487-C A method for producing ethylene homo-and co-polymer SAMSUNG ATOFINA CO LTD (KR) 2005-02-16 CN claimed
CN-1454219-A A method for producing ethylene homo-and co-polymer SAMSUNG GENERAL CHEMICALS CO (KR) 2003-11-05 CN claimed
CN-1189487-C A method for producing ethylene homo-and co-polymer SAMSUNG ATOFINA CO LTD (KR) 2005-02-16 CN disclosed
CN-1454219-A A method for producing ethylene homo-and co-polymer SAMSUNG GENERAL CHEMICALS CO (KR) 2003-11-05 CN disclosed
WO-2002072225-A1 HIGH EFFICIENCY SOL-GEL GAS CHROMATOGRAPHY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-09-19 WO disclosed