Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 3/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22410754 | 0.88 | P2RX3 (0.51) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22424242 | 0.84 | MAPT (0.44) | TP53SMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL22424576 | 0.82 | PDE5A (0.44) | CLPPPDE5APDE4APDE4BPDE4C | |
| SCHEMBL22424057 | 0.77 | PNP (0.48) | CLPPPDE5APDE4APDE4BPDE4C | |
| SCHEMBL22717352 | 0.75 | CLPP (0.46) | CLPPTP53POLBMAPTFABP4 | |
| SCHEMBL28984535 | 0.75 | PTGDR2 (0.53) | CLPPTP53ALDH1A1LMNATSHR | |
| SCHEMBL28669319 | 0.71 | CLPP (0.44) | CLPPPDE5ATP53ALDH1A1LMNA | |
| SCHEMBL22424014 | 0.71 | PRLHR (0.51) | CLPPTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22367284 | 0.69 | GAA (0.51) | SMN1; SMN2ALDH1A1LMNAFAAHGAA | |
| SCHEMBL28948269 | 0.69 | KCNK3 (0.44) | PDE4BPDE4DTP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710667-A | Fused cyclic pyrimidinone derivatives for the treatment of HBV infection or HBV induced diseases | 爱尔兰詹森科学公司 | 2021-11-26 | — | — | CN | disclosed |