Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001408 | 0.81 | FDPS (0.38) | DGAT1MMP8 | |
| SCHEMBL19021912 | 0.78 | DGAT1 (0.33) | DGAT1ALDH1A1MMP8 | |
| SCHEMBL8211542 | 0.76 | DGAT1 (0.38) | DGAT1TSHRMMP8 | |
| SCHEMBL13788287 | 0.76 | MMP8 (0.44) | DGAT1TSHRMMP8 | |
| SCHEMBL291019 | 0.75 | — | — | |
| SCHEMBL4124393 | 0.74 | DGAT1 (0.37) | DGAT1MMP8 | |
| SCHEMBL8321933 | 0.74 | DGAT1 (0.41) | DGAT1MMP8 | |
| Hydrochloric Acid SCHEMBL8906366 | 0.73 | KDM4E (0.39) | DGAT1ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL28326930 | 0.72 | DGAT1 (0.35) | DGAT1MMP8 | |
| SCHEMBL8197896 | 0.72 | DGAT1 (0.35) | DGAT1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108738320-B | cGMP modulators for the treatment of cardiovascular diseases | 默沙东公司 | 2021-11-19 | — | — | CN | disclosed |