Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.70 |
| ▸ | RELA | Q04206 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112870 | 0.84 | RAB9A (0.80) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL706884 | 0.83 | RAB9A (0.71) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31571831 | 0.83 | RAB9A (0.71) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| 2-Phenylquinoline SCHEMBL29399739 | 0.82 | RAB9A (0.73) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| 2-Phenylquinoline SCHEMBL44999 | 0.82 | RAB9A (0.73) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL707767 | 0.82 | NPC1 (1.00) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29636725 | 0.82 | NPC1 (1.00) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28841541 | 0.82 | POLB (0.53) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6858674 | 0.81 | NPC1 (0.97) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27610819 | 0.81 | NPC1 (0.97) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929623-A | Synthesis method of 2-arylquinoline compound | 温州医科大学附属口腔医院 | 2022-01-14 | — | — | CN | disclosed |