SCHEMBL28673190

SCHEMBL28673190

COC(=O)C(=CCC(CBr)(OC)OC)NC(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26838901 0.82 CA12 (0.35) CA12CA2CA14
SCHEMBL24298555 0.82 CA12 (0.35) CA12CA2CA14
SCHEMBL29601090 0.79 CA2 (0.33) CA12CA2CA14
SCHEMBL24323964 0.79 CA2 (0.33) CA12CA2CA14
SCHEMBL3863085 0.79 CA12 (0.35) CA12CA2CA14
SCHEMBL19519894 0.76 CTSK (0.33) CA12CA2CA14
SCHEMBL15844236 0.75 DGAT1 (0.35) CA12CA2CA14
SCHEMBL15844237 0.75 DGAT1 (0.35) CA12CA2CA14
SCHEMBL5787436 0.74 DGAT1 (0.38) CA12CA2CA14
SCHEMBL5787433 0.74 DGAT1 (0.38) CA12CA2CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956169-B Synthesis method of compound (I) 无棣融川医药化工科技有限公司 2024-08-20 CN disclosed
CN-113956169-A Synthesis method of compound (I) 无棣融川医药化工科技有限公司 2022-01-21 CN disclosed
CN-113845434-A Synthetic method of avibactam intermediate (I) 无棣融川医药化工科技有限公司 2021-12-28 CN disclosed