Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396264 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1HPGDPOLB | |
| SCHEMBL21952059 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1HPGDPOLB | |
| SCHEMBL28660619 | 0.85 | HPGD (0.53) | ALDH1A1KMT2AMEN1HPGDTP53 | |
| SCHEMBL28666198 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1HPGDTP53 | |
| SCHEMBL28676728 | 0.77 | HPGD (0.53) | ALDH1A1KMT2AMEN1HPGDTP53 | |
| SCHEMBL30278746 | 0.74 | TSHR (0.51) | ALDH1A1KMT2AMEN1HPGDTP53 | |
| SCHEMBL21952088 | 0.74 | TSHR (0.51) | ALDH1A1KMT2AMEN1HPGDTP53 | |
| SCHEMBL21952023 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL31396267 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL28681663 | 0.73 | HPGD (0.56) | ALDH1A1KMT2AMEN1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |
| CN-113677340-A | Compounds that selectively and efficiently inhibit Hakai-mediated ubiquitination as anti-cancer agents | 诺沃亚桑托斯教授基金会 | 2021-11-19 | — | — | CN | disclosed |