SCHEMBL28674136

SCHEMBL28674136

CC(N)(CCN)c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.48
ESR2 Q92731 11/20 0.48
CYP3A4 P08684 3/20 0.48
SLC6A2 P23975 2/20 0.48
LMNA P02545 1/20 0.48
TYR P14679 1/20 0.48
AR P10275 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
ESRRG P62508 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SHBG P04278 1/20 0.45
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18575579 0.89 TAAR1 (0.36) SLC6A2TSHRALDH1A1TAAR1
SCHEMBL7837799 0.82 ESR1 (0.56) ESR1ESR2CYP3A4SLC6A2LMNA
SCHEMBL9838398 0.79 ESR1 (0.48) ESR1ESR2CYP3A4SLC6A2LMNA
SCHEMBL3650440 0.79 KIF11 (0.46) SLC6A2LMNATSHRSLC6A4SLC6A3
SCHEMBL11431197 0.78 TAAR1 (0.52) CYP3A4SLC6A2CYP2C19TAAR1
SCHEMBL10656617 0.78 ESR1 (0.58) ESR1ESR2CYP3A4SLC6A2LMNA
SCHEMBL6674574 0.76 ESR1 (0.48) ESR1ESR2CYP3A4SLC6A2LMNA
Ethylenediamine SCHEMBL28088084 0.76 LMNA (0.76) ESR1ESR2CYP3A4SLC6A2LMNA
Bisphenol A SCHEMBL29127685 0.76 ESR1 (0.76) ESR1ESR2CYP3A4SLC6A2LMNA
SCHEMBL5329248 0.75 ESR1 (0.64) ESR1ESR2CYP3A4SLC6A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110387035-B Demulsifier, preparation method thereof and application thereof in demulsification of thick oil containing asphaltene 中国石油化工股份有限公司 2022-01-04 CN disclosed