Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | ESRRG | P62508 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656617 | 0.86 | ESR1 (0.58) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL8891278 | 0.85 | LMNA (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL17018523 | 0.83 | TSHR (0.50) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL28674136 | 0.82 | ESR1 (0.48) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL5329248 | 0.82 | ESR1 (0.64) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL22397197 | 0.81 | MEN1 (0.54) | CYP3A4LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL30462529 | 0.81 | ALOX15 (0.40) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL22612421 | 0.81 | MEN1 (0.54) | CYP3A4LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL15989875 | 0.81 | MEN1 (0.54) | CYP3A4LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL1455824 | 0.80 | TAAR1 (0.50) | ESR1ESR2CYP3A4SLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140849-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040560-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |