Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28679193 | 0.83 | TRPM8 (0.38) | TRPM8 | |
| SCHEMBL1521541 | 0.76 | HTT (0.48) | TRPM8PDE10ASLC29A1KDM4EALDH1A1 | |
| Methane SCHEMBL28677585 | 0.73 | FLT3 (0.32) | SYK | |
| Methane SCHEMBL28688768 | 0.72 | HCAR3 (0.32) | TRPM8HCAR3 | |
| Methane SCHEMBL28660726 | 0.71 | LRRK2 (0.46) | PDE10AKDM4EALDH1A1HPGDHSD17B10 | |
| Methane SCHEMBL28662647 | 0.69 | L3MBTL1 (0.38) | HCAR3ALDH1A1 | |
| SCHEMBL22860104 | 0.67 | HTT (0.46) | TRPM8HCAR3ALDH1A1HSD17B10SYK | |
| SCHEMBL12877484 | 0.66 | LMNA (0.35) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23142016 | 0.65 | HTT (0.46) | TRPM8HCAR3KDM4EALDH1A1SYK | |
| SCHEMBL23142017 | 0.65 | HTT (0.46) | TRPM8HCAR3KDM4EALDH1A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768775-A | IDH mutant inhibitor and application thereof | 微境生物医药科技(上海)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-113845528-A | IDH mutant inhibitor and application thereof | 微境生物医药科技(上海)有限公司 | 2021-12-28 | — | — | CN | disclosed |