Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659169 | 0.81 | L3MBTL1 (0.47) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL21224439 | 0.80 | CA1 (0.41) | CYP1A2CYP2C19PDE5ASMN1; SMN2MAPT | |
| SCHEMBL28673842 | 0.77 | MEN1 (0.62) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL1358076 | 0.76 | CGAS (0.47) | CYP1A2CYP2C19PDE5ASMN1; SMN2KMT2A | |
| SCHEMBL28515106 | 0.73 | ATP4A (0.55) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL22290987 | 0.73 | MAPK1 (0.47) | CYP1A2CYP2C19PDE5ASMN1; SMN2NPC1 | |
| SCHEMBL706986 | 0.72 | L3MBTL1 (0.44) | CYP1A2CYP2C19SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28526916 | 0.72 | MAPT (0.56) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28939660 | 0.72 | RAB9A (0.56) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28666285 | 0.71 | MEN1 (0.55) | SMN1; SMN2MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444523-A | Compounds as SMARCA2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115484948-A | Compound and use thereof | 福宏治疗公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113645971-A | Compound and use thereof | 福宏治疗公司 | 2021-11-12 | — | — | CN | disclosed |