Fluorene

Fluorene

SCHEMBL28675258

C(OCC1CO1)C1CO1.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.Oc1ccccc1.Oc1ccccc1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
MGLL Q99685 5/20 0.36
TDP1 Q9NUW8 1/20 0.35
SRD5A2 P31213 1/20 0.35
CYP1A2 P05177 1/20 0.35
ADRA2A P08913 1/20 0.35
MAOA P21397 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
SLC6A4 P31645 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28072088 0.90 ALDH1A1 (0.47) ALDH1A1MGLLTDP1
Fluorene SCHEMBL27831385 0.89 TDP1 (0.44) ALDH1A1MGLLTDP1SRD5A2
Fluorene SCHEMBL919560 0.89 TDP1 (0.44) ALDH1A1MGLLTDP1SRD5A2
Biphenyl SCHEMBL29275457 0.86 MGLL (0.45) ALDH1A1MGLLTDP1
Fluorene SCHEMBL28987665 0.86 ALDH1A1 (0.40) ALDH1A1MGLLTDP1
Fluorene SCHEMBL28045968 0.83 SRD5A2 (0.47) ALDH1A1TDP1SRD5A2CYP1A2ADRA2A
Fluorene SCHEMBL4600798 0.83 SRD5A2 (0.47) ALDH1A1TDP1SRD5A2CYP1A2ADRA2A
Resorcinol SCHEMBL16892645 0.82 ALDH1A1 (0.45) ALDH1A1MGLLTDP1
Phenol SCHEMBL6444166 0.82 TDP1 (0.47) ALDH1A1MGLLTDP1
Methacrylic Acid SCHEMBL28450534 0.81 ALDH1A1 (0.46) ALDH1A1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113906063-A Crosslinkable compositions with low viscosity for coatings and materials with high refractive index and high heat deflection temperature 阿科玛法国公司 2022-01-07 CN claimed