Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537243 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2HSD17B10GAALMNAMMP13 | |
| SCHEMBL29808051 | 0.88 | KMT2A (0.55) | SMN1; SMN2GAALMNAMMP13MAPK1 | |
| SCHEMBL23521924 | 0.88 | KMT2A (0.55) | SMN1; SMN2GAALMNAMMP13MAPK1 | |
| SCHEMBL28931232 | 0.86 | KMT2A (0.47) | SMN1; SMN2HSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL23521860 | 0.86 | KMT2A (0.61) | SMN1; SMN2MMP13ALDH1A1CYP3A4HTT | |
| SCHEMBL29819690 | 0.86 | KMT2A (0.61) | SMN1; SMN2MMP13ALDH1A1CYP3A4HTT | |
| SCHEMBL23521747 | 0.85 | CYP2C19 (0.58) | SMN1; SMN2LMNAMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL29536120 | 0.85 | L3MBTL1 (0.56) | SMN1; SMN2LMNACYP3A4MAPK14L3MBTL1 | |
| SCHEMBL29808056 | 0.85 | CYP2C19 (0.58) | SMN1; SMN2LMNAMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL28931229 | 0.85 | L3MBTL1 (0.56) | SMN1; SMN2LMNACYP3A4MAPK14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874375-A | Cyclic amide compounds and methods thereof for the treatment of rabies | 株式会社大分大学先端医学研究所 | 2021-12-31 | — | — | CN | disclosed |