Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521860 | 1.00 | KMT2A (0.61) | KMT2ASMN1; SMN2HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL28931232 | 0.88 | KMT2A (0.47) | KMT2ASMN1; SMN2HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL28931229 | 0.87 | L3MBTL1 (0.56) | KMT2ASMN1; SMN2L3MBTL1MAPTCYP3A4 | |
| SCHEMBL29536120 | 0.87 | L3MBTL1 (0.56) | KMT2ASMN1; SMN2L3MBTL1MAPTCYP3A4 | |
| SCHEMBL23521747 | 0.87 | CYP2C19 (0.58) | KMT2ASMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL29808056 | 0.87 | CYP2C19 (0.58) | KMT2ASMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL23521924 | 0.86 | KMT2A (0.55) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1HTT | |
| SCHEMBL29808051 | 0.86 | KMT2A (0.55) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1HTT | |
| SCHEMBL28675585 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1HTTMMP2 | |
| SCHEMBL29537243 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1HTTMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | disclosed |
| CN-112839944-B | Compounds and methods for treating rabies | 株式会社大分大学先端医学研究所 | 2022-08-05 | — | — | CN | disclosed |