Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521747 | 1.00 | CYP2C19 (0.58) | CYP2C19HPGDCYP2C9CYP1A2NPSR1 | |
| SCHEMBL29819690 | 0.87 | KMT2A (0.61) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28931232 | 0.87 | KMT2A (0.47) | CYP2C19HPGDCYP2C9CYP1A2NPSR1 | |
| SCHEMBL23521860 | 0.87 | KMT2A (0.61) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28931229 | 0.85 | L3MBTL1 (0.56) | CYP2C19CYP1A2KMT2ALMNAMAPT | |
| SCHEMBL29536120 | 0.85 | L3MBTL1 (0.56) | CYP2C19CYP1A2KMT2ALMNAMAPT | |
| SCHEMBL23521924 | 0.85 | KMT2A (0.55) | KMT2ALMNATSHRALDH1A1MAPK1 | |
| SCHEMBL29537243 | 0.85 | SMN1; SMN2 (0.57) | LMNAALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL28675585 | 0.85 | SMN1; SMN2 (0.57) | LMNAALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL29808051 | 0.85 | KMT2A (0.55) | KMT2ALMNATSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | disclosed |
| CN-115052661-A | Compound and drug using the same | 株式会社大分大学先端医学研究所 | 2022-09-13 | — | — | CN | disclosed |
| CN-112839944-B | Compounds and methods for treating rabies | 株式会社大分大学先端医学研究所 | 2022-08-05 | — | — | CN | disclosed |