Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819690 | 0.88 | KMT2A (0.61) | KMT2ASMN1; SMN2KDM1AHDAC1HPGD | |
| SCHEMBL23521860 | 0.88 | KMT2A (0.61) | KMT2ASMN1; SMN2KDM1AHDAC1HPGD | |
| SCHEMBL29536120 | 0.87 | L3MBTL1 (0.56) | KMT2ASMN1; SMN2CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL29808056 | 0.87 | CYP2C19 (0.58) | KMT2ASMN1; SMN2HPGDCYP1A2CYP2C9 | |
| SCHEMBL23521747 | 0.87 | CYP2C19 (0.58) | KMT2ASMN1; SMN2HPGDCYP1A2CYP2C9 | |
| SCHEMBL28931229 | 0.87 | L3MBTL1 (0.56) | KMT2ASMN1; SMN2CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL23521924 | 0.86 | KMT2A (0.55) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL29808051 | 0.86 | KMT2A (0.55) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL28675585 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL29537243 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12310955-B2 | Cyclic amide compounds for rabies treatment and method thereof | IRIMAJIRI THERAPEUTICS INC. (JP) | 2025-05-27 | — | — | US | disclosed |
| US-20220331300-A1 | CYCLIC AMIDE COMPOUNDS FOR RABIES TREATMENT AND METHOD THEREOF | IRIMAJIRI THERAPEUTICS INC. (JP) | 2022-10-20 | — | — | US | disclosed |
| EP-3978076-A1 | CYCLIC AMIDE COMPOUNDS FOR RABIES TREATMENT AND METHOD THEREOF | Oita University Institute of Advanced Medicine, Inc. (JP) | 2022-04-06 | — | — | EP | disclosed |
| CN-113874375-A | Cyclic amide compounds and methods thereof for the treatment of rabies | 株式会社大分大学先端医学研究所 | 2021-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220331300-A1 | CYCLIC AMIDE COMPOUNDS FOR RABIES TREATMENT AND METHOD THEREOF | F12, RXFP3, AVPR1B | KMT2A 1818/4885SMN1; SMN2 1288/4885KDM1A 573/4885 |
| US-12310955-B2 | Cyclic amide compounds for rabies treatment and method thereof | F12, RXFP3, AVPR1B | KMT2A 1818/4885SMN1; SMN2 1288/4885KDM1A 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.