Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675818 | 0.90 | PARP10 (0.49) | PARP10LMNALTA4HNR5A1PRSS1 | |
| SCHEMBL6681976 | 0.83 | MET (0.48) | NR1H2LMNAMEN1MAPTKMT2A | |
| SCHEMBL6683181 | 0.80 | GAA (0.50) | PARP10MAPTGAANPSR1 | |
| SCHEMBL29226861 | 0.79 | ESR1 (0.47) | LMNAMEN1KMT2ALTA4HSMN1; SMN2 | |
| SCHEMBL28993960 | 0.76 | NPC1 (0.50) | PARP10LMNAMEN1MAPTKMT2A | |
| SCHEMBL881472 | 0.75 | L3MBTL1 (0.58) | PARP10MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL16502888 | 0.75 | MEN1 (0.54) | PARP10LMNAMEN1MAPTKMT2A | |
| SCHEMBL12517383 | 0.75 | NR1H2 (0.52) | NR1H2LMNALTA4HNR5A1 | |
| SCHEMBL28634217 | 0.75 | CA2 (0.46) | NR1H2LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5703994 | 0.75 | PARP10 (0.47) | PARP10LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |