Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 7/20 | 0.68 |
| ▸ | ERCC4 | Q92889 | 7/20 | 0.68 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.62 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.62 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108628 | 0.89 | ERCC1 (0.79) | ERCC1ERCC4TAOK1TAOK3MEN1 | |
| SCHEMBL28676238 | 0.88 | GRIN1 (0.53) | ERCC1ERCC4TAOK1TAOK3ADAMTS5 | |
| SCHEMBL9265107 | 0.83 | LMNA (0.66) | TAOK1TAOK3ADAMTS5HTTALDH1A1 | |
| SCHEMBL28668952 | 0.83 | KMT2A (0.68) | ERCC1ERCC4TAOK1TAOK3ADAMTS5 | |
| SCHEMBL14644570 | 0.79 | HPGD (0.68) | ERCC1ERCC4ADAMTS5ALDH1A1MEN1 | |
| SCHEMBL28656126 | 0.78 | TAOK1 (0.48) | ERCC1ERCC4TAOK1TAOK3ADAMTS5 | |
| SCHEMBL14422166 | 0.77 | TAOK1 (1.00) | ERCC1ERCC4TAOK1TAOK3ADAMTS5 | |
| SCHEMBL140079 | 0.76 | ERCC1 (0.59) | ERCC1ERCC4HTTALDH1A1MEN1 | |
| SCHEMBL5276761 | 0.76 | GRIN1 (0.59) | TAOK1TAOK3ADORA1ADORA2BGRIN1 | |
| SCHEMBL28654035 | 0.75 | ALDH1A1 (0.77) | TAOK1TAOK3ADAMTS5HTTGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |