Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.48 |
| ▸ | ADH1C | P00326 | 1/20 | 0.48 |
| ▸ | ADH1A | P07327 | 1/20 | 0.48 |
| ▸ | ADH7 | P40394 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654 | 0.87 | MEN1 (0.78) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL5799878 | 0.87 | MEN1 (0.78) | MEN1KMT2ATDP1MAOACHRM2 | |
| Benzene SCHEMBL11697595 | 0.87 | MEN1 (0.78) | MEN1KMT2ATDP1MAOACHRM2 | |
| Ammonia Solution, Strong SCHEMBL2064651 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| Bromide SCHEMBL998627 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| Fluoride SCHEMBL634375 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| Water SCHEMBL11666905 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL1862144 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL21550054 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL3990993 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504521-B2 | Methods for the preparation of pyrrolotriazine compounds | BRISTOL-MYERS SQUIBB CO. (US) | 2009-03-17 | — | — | US | disclosed |
| US-20060030708-A1 | Methods for the preparation of pyrrolotriazine compounds | BRISTOL-MYERS SQUIBB COMPANY | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030708-A1 | Methods for the preparation of pyrrolotriazine compounds | SDHB, SDHA, DHPS | MEN1 1100/4885KMT2A 1122/4885TDP1 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.