Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP10 | Q14694 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865955 | 0.90 | ALDH1A1 (0.33) | FBP1ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL2859137 | 0.85 | PDCD1 (0.32) | PDCD1CD274ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2867795 | 0.84 | ADRA1B (0.34) | PDCD1CD274ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2156447 | 0.79 | RAF1 (0.40) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL2987902 | 0.76 | LMNA (0.45) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL2868302 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL2157797 | 0.73 | LMNA (0.37) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL2859156 | 0.72 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4ECYP1A2MAPT | |
| SCHEMBL2156283 | 0.71 | PTPN1 (0.37) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL2986582 | 0.71 | PTGS2 (0.42) | ALDH1A1KDM4ECYP1A2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659263-B2 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20060167246-A1 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167246-A1 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | TPMT, JAK2, GTF3C5 | FBP1 1777/4885PDCD1 566/4885CD274 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.