Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9868799 | 0.87 | — | — | |
| Iodide SCHEMBL28252962 | 0.87 | — | — | |
| Water SCHEMBL28829372 | 0.87 | — | — | |
| Potassium Ion SCHEMBL8525551 | 0.87 | — | — | |
| Potassium Ion SCHEMBL4377601 | 0.87 | — | — | |
| Potassium Ion SCHEMBL27905086 | 0.87 | — | — | |
| SCHEMBL3408563 | 0.82 | — | — | |
| SCHEMBL31122202 | 0.82 | — | — | |
| SCHEMBL208 | 0.82 | — | — | |
| Potassium Ion SCHEMBL8809048 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122555-A1 | S1P 1 RECEPTOR AGONISTS AND USES THEREOF | VALO HEALTH, INC. (US) | 2025-06-12 | — | — | WO | claimed |
| CN-109935848-A | A kind of composite catalyst and preparation method thereof | 中国科学院大连化学物理研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-105541891-B | Ba Rui prepares methods of the Ba Rui for Buddhist nun for intermediate of Buddhist nun and preparation method thereof and by the intermediate | 东南大学 | 2017-11-28 | — | — | CN | disclosed |
| US-7691898-B2 | Phosphonic acid derivatives and the treating agents of diseases related hyperphosphatemia | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-06 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| EP-1962847-A2 | PYRIDINYL SULFONAMIDE MODULATORS OF CHEMOKINE RECEPTORS | GLAXO GROUP LIMITED (GB) | 2008-09-03 | — | — | EP | disclosed |
| EP-1955999-A1 | METHOD FOR PRODUCING VITAMIN D DERIVATIVE BY USING CONVERGENT METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20080119441-A1 | Phosphonic Acid Derivatives and the Treating Agents of Diseases Related Hyperphosphatemia | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1813620-A1 | PHOSPHONIC ACID DERIVATIVE AND THERAPEUTIC AGENT FOR DISEASE IN WHICH HIGH PHOSPHATE LEVEL IN BLOOD PARTICIPATES | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2007067875-A2 | PYRIDINYL SULFONAMIDE MODULATORS OF CHEMOKINE RECEPTORS | GLAXO GROUP LIMTED (GB) | 2007-06-14 | — | — | WO | disclosed |
| EP-1063228-B1 | CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND USE | TAKEDA PHARMACEUTICAL (JP) | 2005-01-19 | — | — | EP | disclosed |
| US-20030153604-A1 | Substituted (aminoiminomethyl or aminomethyl) benzoheteroaryl compounds | AVENTIS PHARMACEUTICALS INC. | 2003-08-14 | — | — | US | disclosed |
| US-6541505-B1 | Inhibiting the activity of Factor Xa; treating a disease state associated with a physiologically detrimental excess amount of thrombin. | AVENTIS PHARMACEUTICALS INC. | 2003-04-01 | — | — | US | disclosed |
| US-6509341-B1 | The invention relates to carboxylic acid derivatives of formula (I), wherein the substituents have the meaning as commented in the description. It also relates to the production and use of same as endothelin receptor antagonists. | ABBOTT LABORATORIES | 2003-01-21 | — | — | US | disclosed |
| US-6388096-B2 | MICROBIOCIDES AGAINST PLANT DISEASE | LG CHEMICAL LTD. (KR) | 2002-05-14 | — | — | US | disclosed |
| EP-1140901-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6262291-B1 | CHEMICAL INTERMEDIATE FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| US-6169182-B1 | REACTING SUBSTITUTED N-(CYANOPHENYL)AMINOALKENAMIDES WITH CARBONIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-02 | — | — | US | disclosed |
| WO-2000039087-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-06 | — | — | WO | disclosed |
| US-4234596-A | ISOMERS OF THIENAMYCIN | MERCK & CO., INC. (US) | 1980-11-18 | — | — | US | disclosed |