Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670367 | 0.95 | CA1 (0.34) | CA1CA2CA4CA7CA9 | |
| Potassium Ion SCHEMBL28579061 | 0.95 | CA1 (0.34) | CA1CA2CA4CA7CA9 | |
| Lithium Ion SCHEMBL28760036 | 0.77 | LMNA (0.47) | TP53 | |
| Lithium Ion SCHEMBL10624523 | 0.75 | TP53 (0.31) | TP53 | |
| Lithium Ion SCHEMBL28670483 | 0.75 | CA1 (0.36) | CA1CA2CA9TP53 | |
| SCHEMBL8912263 | 0.74 | — | — | |
| SCHEMBL26976755 | 0.72 | ALDH1A1 (0.47) | TP53 | |
| SCHEMBL1308988 | 0.72 | ALDH1A1 (0.47) | TP53 | |
| SCHEMBL23530434 | 0.70 | CA1 (0.36) | CA1CA2CA9TP53 | |
| SCHEMBL4430233 | 0.70 | ENPEP (0.40) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113769592-B | Quaternized modified polyarylether membrane material and preparation method and application thereof | 吉林大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113769592-A | Quaternized modified polyarylether membrane material and preparation method and application thereof | 吉林大学 | 2021-12-10 | — | — | CN | claimed |
| CN-113769592-B | Quaternized modified polyarylether membrane material and preparation method and application thereof | 吉林大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113769592-A | Quaternized modified polyarylether membrane material and preparation method and application thereof | 吉林大学 | 2021-12-10 | — | — | CN | disclosed |